Senior Scientist, Instrument Operation

Location: Austin, Texas, United States

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Requisition Number: 3189

Position Title: Senior Scientist, Instrument Operation

External Description:

SUMMARY:  The Senior Scientist, Instrument Operation, under the guidance of the Leader of Instrument Operation is responsible for performing LC-MS-MS analysis with high efficiency and accuracy following Worldwide Clinical Trials (Worldwide) and Sponsor requirements. This individual is a key member of the instrument operations team with a strong knowledge of mass spectrometry and HPLC techniques.  They may assist other operation, validation, and method development staff with projects and instrument troubleshooting in addition to recommending and implementing laboratory improvements. A Senior Scientist participates in the production of scientific literature such as posters, presentations and publications.  

Tasks may include but are not limited to:

  • Accomplish all necessary and applicable Worldwide training, including Standard Operating Procedures, Corporate Handbook, and Health and Safety Manual
  • Understand and apply GLP guidelines in all aspects of work
  • Perform LC-MS-MS analysis following procedures specified by established test methods
  • Monitor system performance to ensure quality of results
  • Process data following Worldwide procedures and guidelines
  • Document promptly and clearly all procedures
  • Maintain and calibrate instruments and equipment as required
  • May serve as a Lab Monitor
  • Make scientific judgments regarding the quality and integrity of data, taking corrective action, and documenting the decision
  • Serve as a mentor for less experienced members of the instrument operations team
  • Assist method development and validation scientists with instrument hardware or method issues when needed
  • Ensuring quality of deliverables including data, reports, and electronic files
  • Communicating effectively internally and externally with all levels of personnel

Perform other duties as assigned.  The duties and responsibilities listed above are representative of the nature and level of work assigned and are not necessarily all-inclusive.

  • Ability to understand complex written and verbal instructions.
  • Must be able to work well with a variety of laboratory personnel.
  • Must have excellent attention to detail. Must be familiar with all required software.
  • Must be able to set up and operate instruments, LC pumps and auto-samplers.
  • Extensive experience in performing analytical tests
  • Should develop and demonstrate effective time management and be able to manage their time in order to meet tasks, budgets and deadlines. If unforeseen problems occur, these should be communicated to their supervisor or other management personnel.


  • Bachelor’s degree with a science discipline
  • Eight or more years of relevant work experience required


State: Texas

Employment Type: Regular

Community / Marketing Title: Senior Scientist, Instrument Operation

Company Profile:

We’re a global, mid-size CRO that pushes boundaries, innovates and invents — because the path to a cure for the world’s most persist diseases is not paved by those who play it safe, but by those who take pioneering, creative approaches, and implement them with quality and excellence. We are experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs, in the best possible way.

Location_formattedLocationLong: Austin, Texas US

CountryEEOText_Description: Worldwide Clinical Trials is an equal opportunity employer, dedicated to a policy of non-discrimination in employment on any basis including age, sex, color, race, creed, national origin, religion, marital status, sexual orientation, political belief or disability.

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